For angiofbiroma of small lesions, external surgical approaches are gradually being replaced by endoscopic surgery, which can also be combined with conventional approaches in cases of more advanced disease. Juvenile nasopharyngeal angiofibroma with orbital extension. The typical patient is an adolescent male with a clinical history of recurrent epistaxis and nasal obstruction. Juvenile nasopharyngeal angiofibroma jna represents. The evidence from these studies indicates that angiofibroma takes origin in the pterygopalatine fossa at the aperture of the pterygoid vidian canal. Pdf juvenile nasopharyngeal angiofibroma is tumour almost exclusively seen in adolescent males, constituting less than 1% of all. Juvenile nasopharyngeal angiofibroma radiology reference.
Juvenile nasopharyngeal angiofibroma is a rare, highly luiz a cr, romualdo s lt, fava a. Juvenile nasopharyngeal angiofibroma knowledge for. The most common presenting symptom is painless nasal obstruction or epistaxis. Evolution of management article pdf available in international journal of pediatrics 201222. Epidemiology juvenile nasopharyngeal angiofibromas. The tumor contains many blood vessels and spreads within the area in which it. Pdf it is presented a case of juvenile nasopharyngeal angiofibroma in a patient with this pathology, from the clicial practice no. Juvenile nasopharyngeal angiofibroma jna is a relatively rare tumor of the nasopharynx, comprising only 0. Vessels are thinwalled, lack elastic fibers, have absent or incomplete smooth muscle, and vary in appearance from stellate or staghorn to barely conspicuous because of stromal compression. Nasopharyngeal angiofibroma introduction juvenile nasopharyngeal angiofibroma jna is a benign, but locally aggressive and extremely vascular head and neck neoplasm, occurring almost exclusively in the nasopharynx of adolescent males. Two types of lateral extension in juvenile nasopharyngeal angiofibroma. Clinical case a male, 21 years of age, without relevant history, presented with left exophthalmos and diplopia in extreme gaze positions with 2 weeks evolution, without clinic.
In 1906 chareau revived the interest in the study of juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma jna is a rare tumor in adolescent males. Request pdf juvenile nasopharyngeal angiofibroma juvenile. Juvenile nasopharyngeal angiofibroma jna onset most commonly is in the second decade. Though it is a benign tumor, it is locally invasive and can invade the nose, cheek, orbit. Angiofibroma juvenil nasofaringeo scielo cuba infomed. Clusters of rounded, epithelioid cells, often around vessels. The typical symptoms of juvenile nasopharyngeal angiofibroma are chronic nasal.
Juvenile nasopharyngeal angiofibroma has been documented since the time of hippocrates 4 bc. Nasoangiofibroma youth is a highly vascularized tumor almost exclusively male adolescents presentation. Some surgeons, however, do not routinely perform embolization preoperatively, finding that embolization is justified only in larger tumors therefore, all cases corresponded to snyderman grade iv table 4. It is the most common benign tumor of the nasopharnyx but only accounts for less than 0. Well circumscribed but unencapsulated polypoid fibrous mass, bleeds severely on manipulation and biopsy, may occlude nares. Juvenile nasopharyngeal angiofibroma electronic journal of. The jna juvenile nasopharyngeal angiofibroma is a rare neoplasm, of benign. To the best of our knowledge, this is the first such case reported in the literature. A sevenyear experience with patients with juvenile nasopharyngeal. Angiofibroma nasofaring juvenile free download as pdf file. Shaheen in 1930 reported the first female patient with juvenile nasopharyngeal.
Juvenile nasopharyngeal angiofibroma is a pathologically benign yet locally aggressive and destructive vascular lesion of head and neck region typically affecting adolescent boys. Download fulltext pdf download fulltext pdf juvenile angiofibroma. Acessos cirurgicos no angiofibroma nasofaringeo juvenil relato. Although the use of nonsurgical therapies is described in the literature, surgery is currently considered the ideal treatment for. Intricate mixture of stellate and staghorn blood vessels with variable vessel wall thickness ranging from single layer of endothelium to variable smooth muscle coat.
Juvenile nasopharyngeal angiofibroma is a rare, highly vascular, and. A very rare case of juvenile angiofibroma arising from the nasal septum is reported. Juvenile nasopharyngeal angiofibroma jna is a benign neoplasm of the nasopharynx. Juvenile nasopharyngeal angiofibroma radiology case. Ppt journal juvenile nasopharynx angiofibroma free download as powerpoint presentation. Patterns of vascularization and surgical morbidity in juvenile nasopharyngeal angiofibroma. Retrospective, descriptive study conducted after approval from the ethics committee of the federal university of sergipe protocol methods we analyzed 20 patients with nasopharyngeal angiofibroma who underwent surgery in the otolaryngology service between and nasofarngro tumour of the respiratory system. In the general population, jna occurs at an incidence of roughly 1. Fw110 grey wolf pdf the tumor invades the nasal sinuses or the pterygomaxillary fossa with bone destruction. Nasopharyngeal angiofibroma is usually encapsulated and composed of vascular tissue and fibrous stroma with coarse or fine collagen fibers. Although a histopathologically benign tumor of vascular origin, jna behaves locally invasive and. Dsa digital subtraction angiography of carotid artery to see the extension of. Juvenile nasopharyngeal angiofibroma jna is a rare and benign but locally aggressive fibrovascular tumor arising from the posterolateral wall of the. Juvenile nasopharyngeal angiofibroma is a rare, highly luiz a cr, romualdo s lt, fava a s.
Juvenile nasoangiofibroma is a benign tumor that grows. Angiofibroma juvenil pdf juvenile nasopharyngeal angiofibromas jna are a rare benign but locally aggressive vascular tumor. It most commonly affects adolescent males and may grow into fissures of the. This is a classical presentation of juvenile nasopharyngeal angiofibroma. Juvenile angiofibroma jna is a benign tumor that tends to bleed and occurs in the nasopharynx of prepubertal and adolescent males. Endoscopic surgery in treatment of juvenile nasopharyngeal angiofibroma. Nasopharyngeal juvenile angiofibroma resected endoscopically. These tumors are benign, however they are locally invasive. Iiprofessor in the department of head and neck surgery. Juvenile nasopharyngeal angiofibromas jna are a rare benign, but locally aggressive, vascular tumor. Review article nasopharyngeal angiofibroma ashutosh hota. Seventytwo patients with juvenile angiofibroma have been investigated by computerized tomography ct andor magnetic resonance imaging mri over a period of 20 years. The present article is a retrospective study of surgically treated patients of juvenile nasopharyngeal angiofibroma over a period of 5 years.
Juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth patterns. Other names have been used as a nasopharyngeal fibroma, fibroma of the adolescent and bleeding fibroangioma 1. Extranasopharyngeal angiofibroma of uncinate process in a female. As the tumor is largely spaceoccupying and highly vascular, patients typically. Nasopharyngeal angiofibroma is a histologically benign but locally aggressive vascular tumor of the nasopharynx that arises from the superior margin of the sphenopalatine foramen and grows in the back of the nasal cavity. Angiofibroma nasofaringeo juvenil linkedin slideshare.
This tumour was ablated with surgical manipulation and electrocauterization. It most commonly affects adolescent males because it is a hormonesensitive. Mean age at diagnosis is 14 years may regress in late teens but may persist into adulthood rare in patients older than 25 years. Jnas originate from the posterior choanal tissues and rapidly extend into the surrounding regions, including the nasopharynx, the orbits, and even the intracranial cavity. Ppt journal juvenile nasopharynx angiofibroma radiation. It is presented a case of juvenile nasopharyngeal angiofibroma in a patient with this pathology, from the clicial practice no. The case of a patient with orbit involvement and intracranial extension due to intracranial extension of nasopharyngeal angiofibroma with ethmoidal origin is presented. Infact hippocrates goes on to describe a polyp in the nose which weeped blood. Juvenile nasopharyngeal angiofibroma is a rare, highly vascular.
Juvenile nasopharyngeal angiofibroma is a rare, highly. The tumors are frequently located in the posterolateral wall of the nasal cavity. This is a histologically benign lesion with very aggressive local behavior. Juvenile nasopharyngeal angiofibromas occur almost exclusively in males and usually in adolescence 15 years. Juvenile nasopharyngeal angiofibroma naj is a tumor with vascular component, slow growing, benign but very aggressive because of its local invasiveness. Pdf juvenile angiofibroma is a rare benign lesion originating from the pterygopalatine fossa with distinctive epidemiologic features and growth. A concise classification system and appropriate treatment options. It most commonly affects adolescent males because it is a hormonesensitive tumor. Management of juvenile nasopharyngeal angiofibroma. Juvenile nasopharyngeal angiofibroma jna is a rare, benign, but locally aggressive tumor occurring almost exclusively in adolescent males. It is almost exclusicely encountered in adolescent males 1. This is a pdf file of an unedited manuscript that has been accepted for.
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